Differences in plasma and sputum biomarkers between COPD and COPD-asthma overlap
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چکیده
منابع مشابه
Differences in plasma and sputum biomarkers between COPD and COPD-asthma overlap.
The pathophysiological features of chronic obstructive pulmonary disease (COPD)-asthma overlap are poorly understood and there has been no study of plasma or sputum biomarkers in overlap patients. In order to clarify the similarity and differences between overlap and COPD or asthma, we have investigated four potential biomarkers of COPD: surfactant protein A (SP-A), soluble receptor for advance...
متن کاملSputum cell count: biomarkers in the differentiation of asthma, COPD and asthma–COPD overlap
INTRODUCTION Cell count in induced sputum is a noninvasive biomarker to assess airway inflammation phenotypes. Accordingly, sputum cell counts are extensively used in the treatment of asthma and COPD. Nevertheless, the clinical application of sputum cell counts in patients with asthma-COPD overlap (ACO) remains elusive. The aim of this study was to investigate sputum cell counts in patients wit...
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Asthma-COPD overlap syndrome (ACOS) is a commonly encountered chronic airway disease. However, ACOS is still a consensus-based clinical phenotype and the underlying inflammatory mechanisms are inadequately characterized. To clarify the inflammatory mediatypical for ACOS, five biomarkers, namely interleukin (IL)-13, myeloperoxidase (MPO), neutrophil gelatinase-associated lipocalin (NGAL), chitin...
متن کاملCharacterization of sputum biomarkers for asthma–COPD overlap syndrome [Erratum]
[This corrects the article on p. 2457 in vol. 11, PMID: 27757028.].
متن کاملInflammatory biomarkers in asthma-COPD overlap syndrome
BACKGROUND The clinical phenotypes and underlying mechanisms of asthma-COPD overlap syndrome (ACOS) remain elusive. This study aimed to investigate a comparison of COPD patients with and without ACOS, focusing on inflammatory biomarkers, in an outpatient COPD cohort. METHODS We conducted a cross-sectional study analyzing prospectively collected data from the Ishinomaki COPD Network registry. ...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2013
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.00024313